Ribosomal back translocase

The Basics
The crystallographic asymmetric unit of the solved structure (3cb4) contains 6 monomers of LepA.

The LepA monomer.

LepA and EF-G Are Similar
The high degree of sequence similarity between LepA and EF-G is reflected in the structural similarity between the individual homologous domains of LepA and EF-G. The domains are colored according to figure 1 of the paper describing the structure.

Overall superposition of LepA and EF-G. Note that the individual domains of LepA and EF-G, such as III V, superimpose much better when done separately (shown in figure 2 of the paper describing the structure).

PDB Entry
3cb4 is a 6 chains structure of sequences from Escherichia coli k12. Full crystallographic information is available from OCA.

Related Structures and Topics

 * Ef-G
 * The Ribosome
 * 70S ribosome bound to EF-G: 2wri, 2wrj, 2wrk, 2wrl
 * For additional information, see: Translation

Reference
 Page begun with original page seeded for PDB entry 3cb4 by OCA on Wed Jun 3 08:45:42 2009